1CP3
CRYSTAL STRUCTURE OF THE COMPLEX OF APOPAIN WITH THE TETRAPEPTIDE INHIBITOR ACE-DVAD-FMC
Summary for 1CP3
Entry DOI | 10.2210/pdb1cp3/pdb |
Related PRD ID | PRD_000239 |
Descriptor | APOPAIN, ACETYL-ASP-VAL-ALA-ASP-FLUOROMETHYLKETONE (3 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, apoptosis, interleukin-1beta-converting enzyme, cysteine-protease, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P42574 |
Total number of polymer chains | 4 |
Total formula weight | 64196.73 |
Authors | Mittl, P.R.E.,Dimarco, S.,Gruetter, M.G. (deposition date: 1996-12-12, release date: 1997-12-24, Last modification date: 2012-12-12) |
Primary citation | Mittl, P.R.,Di Marco, S.,Krebs, J.F.,Bai, X.,Karanewsky, D.S.,Priestle, J.P.,Tomaselli, K.J.,Grutter, M.G. Structure of recombinant human CPP32 in complex with the tetrapeptide acetyl-Asp-Val-Ala-Asp fluoromethyl ketone. J.Biol.Chem., 272:6539-6547, 1997 Cited by PubMed: 9045680DOI: 10.1074/jbc.272.10.6539 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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