1CKW

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR: SOLUTION STRUCTURES OF PEPTIDES BASED ON THE PHE508 REGION, THE MOST COMMON SITE OF DISEASE-CAUSING DELTA-F508 MUTATION

1CKW の概要

• エントリーDOI: 10.2210/pdb1ckw/pdb
• NMR情報: BMRB: 4595
• 分子名称: PROTEIN (CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR (CFTR)) (1 entity in total)
• 機能のキーワード: p25_tfe, cystic fibrosis, peptides, metal transport
• 細胞内の位置: Early endosome membrane; Multi-pass membrane protein (By similarity): Q00555
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 2907.35

構造登録者

Massiah, M.A.,Ko, Y.H.,Pedersen, P.L.,Mildvan, A.S. (登録日: 1999-04-26, 公開日: 1999-05-04, 最終更新日: 2023-12-27)

• 主引用文献: Massiah, M.A.,Ko, Y.H.,Pedersen, P.L.,Mildvan, A.S.; Cystic fibrosis transmembrane conductance regulator: solution structures of peptides based on the Phe508 region, the most common site of disease-causing DeltaF508 mutation.; Biochemistry, 38:7453-7461, 1999; PubMed: 10360942; DOI: 10.1021/bi9903603

実験手法

SOLUTION NMR