1CIZ
X-RAY STRUCTURE OF HUMAN STROMELYSIN CATALYTIC DOMAIN COMPLEXES WITH NON-PEPTIDE INHIBITORS: IMPLICATION FOR INHIBITOR SELECTIVITY
1CIZ の概要
エントリーDOI | 10.2210/pdb1ciz/pdb |
分子名称 | PROTEIN (STROMELYSIN-1), ZINC ION, CALCIUM ION, ... (6 entities in total) |
機能のキーワード | matrix metalloproteinase, mmp-3, non-peptide inhibitor, metalloproteinase |
由来する生物種 | Homo sapiens (human) |
細胞内の位置 | Secreted, extracellular space, extracellular matrix : P08254 |
タンパク質・核酸の鎖数 | 1 |
化学式量合計 | 19737.76 |
構造登録者 | Pavlovsky, A.G.,Williams, M.G.,Ye, Q.-Z.,Ortwine, D.F.,Purchase II, C.F.,White, A.D.,Dhanaraj, V.,Roth, B.D.,Johnson, L.L.,Hupe, D.,Humblet, C.,Blundell, T.L. (登録日: 1999-04-06, 公開日: 1999-09-01, 最終更新日: 2023-08-09) |
主引用文献 | Pavlovsky, A.G.,Williams, M.G.,Ye, Q.Z.,Ortwine, D.F.,Purchase II, C.F.,White, A.D.,Dhanaraj, V.,Roth, B.D.,Johnson, L.L.,Hupe, D.,Humblet, C.,Blundell, T.L. X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity. Protein Sci., 8:1455-1462, 1999 Cited by PubMed: 10422833主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (1.64 Å) |
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