1CIL

THE POSITIONS OF HIS-64 AND A BOUND WATER IN HUMAN CARBONIC ANHYDRASE II UPON BINDING THREE STRUCTURALLY RELATED INHIBITORS

1CIL の概要

• エントリーDOI: 10.2210/pdb1cil/pdb
• 分子名称: CARBONIC ANHYDRASE II, ZINC ION, (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE, ... (4 entities in total)
• 機能のキーワード: lyase(oxo-acid)
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P00918
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29547.71

構造登録者

Smith, G.M.,Alexander, R.S.,Christianson, D.W.,Mckeever, B.M.,Ponticello, G.S.,Springer, J.P.,Randall, W.C.,Baldwin, J.J.,Habecker, C.N. (登録日: 1993-10-20, 公開日: 1994-01-31, 最終更新日: 2024-02-07)

• 主引用文献: Smith, G.M.,Alexander, R.S.,Christianson, D.W.,McKeever, B.M.,Ponticello, G.S.,Springer, J.P.,Randall, W.C.,Baldwin, J.J.,Habecker, C.N.; Positions of His-64 and a bound water in human carbonic anhydrase II upon binding three structurally related inhibitors.; Protein Sci., 3:118-125, 1994; PubMed: 8142888

実験手法

X-RAY DIFFRACTION (1.6 Å)