1C72

TYR115, GLN165 AND TRP209 CONTRIBUTE TO THE 1,2-EPOXY-3-(P-NITROPHENOXY)PROPANE CONJUGATING ACTIVITIES OF GLUTATHIONE S-TRANSFERASE CGSTM1-1

1C72 の概要

• エントリーDOI: 10.2210/pdb1c72/pdb
• 分子名称: PROTEIN (GLUTATHIONE S-TRANSFERASE), 1-HYDROXY-2-S-GLUTATHIONYL-3-PARA-NITROPHENOXY-PROPANE (3 entities in total)
• 機能のキーワード: glutathione s-transferase, 1, 2-epoxy-3-(p-nitrophenoxy)propane, epoxidase activity, steady-state kinetics, transferase
• 由来する生物種: Gallus gallus (chicken)
• 細胞内の位置: Cytoplasm: P20136
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 105128.58

構造登録者

Chern, M.K.,Wu, T.C.,Hsieh, C.H.,Chou, C.C.,Liu, L.F.,Kuan, I.C.,Yeh, Y.H.,Hsiao, C.D.,Tam, M.F. (登録日: 2000-02-02, 公開日: 2000-08-30, 最終更新日: 2023-08-09)

• 主引用文献: Chern, M.K.,Wu, T.C.,Hsieh, C.H.,Chou, C.C.,Liu, L.F.,Kuan, I.C.,Yeh, Y.H.,Hsiao, C.D.,Tam, M.F.; Tyr115, gln165 and trp209 contribute to the 1, 2-epoxy-3-(p-nitrophenoxy)propane-conjugating activity of glutathione S-transferase cGSTM1-1.; J.Mol.Biol., 300:1257-1269, 2000; PubMed: 10903867; DOI: 10.1006/jmbi.2000.3904

実験手法

X-RAY DIFFRACTION (2.8 Å)