1C57

DIRECT DETERMINATION OF THE POSITIONS OF DEUTERIUM ATOMS OF BOUND WATER IN CONCANAVALIN A BY NEUTRON LAUE CRYSTALLOGRAPHY

1C57 の概要

• エントリーDOI: 10.2210/pdb1c57/pdb
• 分子名称: Concanavalin-Br, MANGANESE (II) ION, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: concanavalin a, neutron laue diffraction, bound d2o molecules, sugar binding protein
• 由来する生物種: Canavalia ensiformis (jack bean)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 25717.40

構造登録者

Habash, J.,Raftery, J.,Nuttall, R.,Price, H.J.,Lehmann, M.S.,Wilkinson, C.,Kalb, A.J.,Helliwell, J.R. (登録日: 1999-10-26, 公開日: 2000-05-08, 最終更新日: 2023-12-27)

主引用文献

Habash, J.,Raftery, J.,Nuttall, R.,Price, H.J.,Wilkinson, C.,Kalb, A.J.,Helliwell, J.R.
Direct determination of the positions of the deuterium atoms of the bound water in -concanavalin A by neutron Laue crystallography.
Acta Crystallogr.,Sect.D, 56:541-550, 2000

PubMed Abstract: The correct positions of the deuterium (D) atoms of many of the bound waters in the protein concanavalin A are revealed by neutron Laue diffraction. The approach includes cases where these water D atoms show enough mobility to render them invisible even to ultra-high resolution synchrotron-radiation X-ray crystallography. The positions of the bound water H atoms calculated on the basis of chemical and energetic considerations are often incorrect. The D-atom positions for the water molecules in the Mn-, Ca- and sugar-binding sites of concanavalin A are described in detail.

PubMed: 10771422
DOI: 10.1107/S0907444900002353

実験手法

NEUTRON DIFFRACTION (2.4 Å)