1C1F

LIGAND-FREE CONGERIN I

Summary for 1C1F

• Entry DOI: 10.2210/pdb1c1f/pdb
• Descriptor: PROTEIN (CONGERIN I) (2 entities in total)
• Functional Keywords: galectin, lectin, beta-galactose-binding, sugar binding protein
• Biological source: Conger myriaster (whitespotted conger)
• Total number of polymer chains: 1
• Total formula weight: 15356.08

Authors

Shirai, T.,Mitsuyama, C.,Niwa, Y.,Matsui, Y.,Hotta, H.,Yamane, T.,Kamiya, H.,Ishii, C.,Ogawa, T.,Muramoto, K. (deposition date: 1999-03-03, release date: 1999-10-08, Last modification date: 2024-10-16)

Primary citation

Shirai, T.,Mitsuyama, C.,Niwa, Y.,Matsui, Y.,Hotta, H.,Yamane, T.,Kamiya, H.,Ishii, C.,Ogawa, T.,Muramoto, K.
High-resolution structure of the conger eel galectin, congerin I, in lactose-liganded and ligand-free forms: emergence of a new structure class by accelerated evolution.
Structure Fold.Des., 7:1223-1233, 1999

PubMed Abstract: Congerin I is a member of the galectin (animal beta-galactoside-binding lectin) family and is found in the skin mucus of conger eel. The galectin family proteins perform a variety of biological activities. Because of its histological localization and activity against marine bacteria and starfish embryos, congerin I is thought to take part in the eels' biological defense system against parasites.

PubMed: 10545323
DOI: 10.1016/S0969-2126(00)80056-8

Experimental method

X-RAY DIFFRACTION (1.6 Å)