1BVR

M.TB. ENOYL-ACP REDUCTASE (INHA) IN COMPLEX WITH NAD+ AND C16-FATTY-ACYL-SUBSTRATE

Summary for 1BVR

Entry DOI	10.2210/pdb1bvr/pdb
Descriptor	PROTEIN (ENOYL-ACYL CARRIER PROTEIN (ACP) REDUCTASE), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRANS-2-HEXADECENOYL-(N-ACETYL-CYSTEAMINE)-THIOESTER, ... (4 entities in total)
Functional Keywords	nadh-dependent enoyl-acp reductase, structural genomics, psi, protein structure initiative, tb structural genomics consortium, tbsgc, oxidoreductase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	6
Total formula weight	175952.44
Authors	Rozwarski, D.A.,Vilcheze, C.,Sugantino, M.,Bittman, R.,Jacobs, W.,TB Structural Genomics Consortium (TBSGC) (deposition date: 1998-09-17, release date: 1999-09-17, Last modification date: 2023-08-09)
Primary citation	Rozwarski, D.A.,Vilcheze, C.,Sugantino, M.,Bittman, R.,Sacchettini, J.C. Crystal structure of the Mycobacterium tuberculosis enoyl-ACP reductase, InhA, in complex with NAD+ and a C16 fatty acyl substrate. J.Biol.Chem., 274:15582-15589, 1999 Cited by PubMed: 10336454 DOI: 10.1074/jbc.274.22.15582 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation