1BUL

6ALPHA-(HYDROXYPROPYL)PENICILLANATE ACYLATED ON NMC-A BETA-LACTAMASE FROM ENTEROBACTER CLOACAE

1BUL の概要

• エントリーDOI: 10.2210/pdb1bul/pdb
• 分子名称: NMC-A BETA-LACTAMASE, 2-(1-CARBOXY-2-HYDROXY-2-METHYL-PROPYL)-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (4 entities in total)
• 機能のキーワード: hydrolase, antibiotic resistance, class a carbapenemase
• 由来する生物種: Enterobacter cloacae
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 30000.64

構造登録者

Mourey, L.,Swaren, P.,Miyashita, K.,Bulychev, A.,Mobashery, S.,Samama, J.P. (登録日: 1998-09-04, 公開日: 1998-12-30, 最終更新日: 2024-04-03)

• 主引用文献: Mourey, L.,Swaren, P.,Miyashita, K.,Bulychev, A.,Mobashery, S.,Samama, J.P.; Inhibition of the Nmc-A B-Lactamase by a Penicillanic Acid Derivative, and the Structural Bases for the Increase in Substrate Profile of This Antibiotic Resistance Enzyme; J.Am.Chem.Soc., 120:9382-9383, 1998

実験手法

X-RAY DIFFRACTION (1.89 Å)