1BTX

Episelection: Novel Ki ~Nanomolar Inhibitors of Serine Proteases Selected by Binding or Chemistry on an Enzyme Surface

Summary for 1BTX

Entry DOI	10.2210/pdb1btx/pdb
Related	1btw 1btz
Related PRD ID	PRD_000389
Descriptor	BETA-TRYPSIN, N-(tert-butoxycarbonyl)-L-alanyl-N-[(1S)-5-amino-1-(diethoxyboranyl)pentyl]-L-valinamide, CALCIUM ION, ... (4 entities in total)
Functional Keywords	tripeptideboronate ethyl ester inhibited, serine proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Bos taurus (cattle)
Cellular location	Secreted, extracellular space: P00760
Total number of polymer chains	1
Total formula weight	24525.46
Authors	Stroud, R.M.,Katz, B.A.,Finer-Moore, J. (deposition date: 1995-05-17, release date: 1995-10-15, Last modification date: 2012-12-12)
Primary citation	Katz, B.A.,Finer-Moore, J.,Mortezaei, R.,Rich, D.H.,Stroud, R.M. Episelection: novel Ki approximately nanomolar inhibitors of serine proteases selected by binding or chemistry on an enzyme surface. Biochemistry, 34:8264-8280, 1995 Cited by PubMed: 7599119 DOI: 10.1021/bi00026a008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation