1BTP

UNIQUE BINDING OF A NOVEL SYNTHETIC INHIBITOR, N-[3-[4-[4-(AMIDINOPHENOXY)-CARBONYL]PHENYL]-2-METHYL-2-PROPENOYL]-N-ALLYLGLYCINE METHANESULFONATE TO BOVINE TRYPSIN, REVEALED BY THE CRYSTAL STRUCTURE OF THE COMPLEX

1BTP の概要

• エントリーDOI: 10.2210/pdb1btp/pdb
• 分子名称: BETA-TRYPSIN, CALCIUM ION (3 entities in total)
• 機能のキーワード: hydrolase (serine proteinase)
• 由来する生物種: Bos taurus (cattle)
• 細胞内の位置: Secreted, extracellular space: P00760
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24053.03

構造登録者

Odagaki, Y.,Nakai, H.,Senokuchi, K.,Kawamura, M.,Hamanaka, N.,Nakamura, M.,Tomoo, K.,Ishida, T. (登録日: 1995-08-11, 公開日: 1996-01-29, 最終更新日: 2011-07-13)

• 主引用文献: Odagaki, Y.,Nakai, H.,Senokuchi, K.,Kawamura, M.,Hamanaka, N.,Nakamura, M.,Tomoo, K.,Ishida, T.; Unique binding of a novel synthetic inhibitor, N-[3-[4-[4-(amidinophenoxy)carbonyl]phenyl]-2-methyl-2-propenoyl]- N-allylglycine methanesulfonate, to bovine trypsin, revealed by the crystal structure of the complex.; Biochemistry, 34:12849-12853, 1995; PubMed: 7548040; DOI: 10.1021/bi00039a046

実験手法

X-RAY DIFFRACTION (2.2 Å)