1BR8
IMPLICATIONS FOR FUNCTION AND THERAPY OF A 2.9A STRUCTURE OF BINARY-COMPLEXED ANTITHROMBIN
Summary for 1BR8
Entry DOI | 10.2210/pdb1br8/pdb |
Descriptor | PROTEIN (ANTITHROMBIN-III), PROTEIN (PEPTIDE) (3 entities in total) |
Functional Keywords | serpins, antithrombin, binary-complex, heparin, polymerisation, thrombosis, emphysema, cirrhosis, blood clotting |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P01008 |
Total number of polymer chains | 3 |
Total formula weight | 99291.23 |
Authors | Skinner, R.,Chang, W.S.W.,Jin, L.,Pei, X.Y.,Huntington, J.A.,Abrahams, J.P.,Carrell, R.W.,Lomas, D.A. (deposition date: 1998-08-26, release date: 1998-09-02, Last modification date: 2023-08-09) |
Primary citation | Skinner, R.,Chang, W.S.,Jin, L.,Pei, X.,Huntington, J.A.,Abrahams, J.P.,Carrell, R.W.,Lomas, D.A. Implications for function and therapy of a 2.9 A structure of binary-complexed antithrombin. J.Mol.Biol., 283:9-14, 1998 Cited by PubMed: 9761669DOI: 10.1006/jmbi.1998.2083 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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