1BMV

PROTEIN-RNA INTERACTIONS IN AN ICOSAHEDRAL VIRUS AT 3.0 ANGSTROMS RESOLUTION

1BMV の概要

• エントリーDOI: 10.2210/pdb1bmv/pdb
• 分子名称: RNA (5'-R(*GP*GP*UP*CP*AP*AP*AP*AP*UP*GP*C)-3'), PROTEIN (ICOSAHEDRAL VIRUS - A DOMAIN), PROTEIN (ICOSAHEDRAL VIRUS - B AND C DOMAIN) (3 entities in total)
• 機能のキーワード: protein-rna complex, single strand, icosahedral virus, virus-rna complex, virus/rna
• 由来する生物種: Bean pod mottle virus; 詳細
• 細胞内の位置: Movement protein: Host cell junction, host plasmodesma (By similarity). Large coat protein: Virion (Potential): P23009 P23009
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 66668.33

構造登録者

Chen, Z.,Stauffacher, C.,Li, Y.,Schmidt, T.,Bomu, W.,Kamer, G.,Shanks, M.,Lomonossoff, G.,Johnson, J.E. (登録日: 1989-10-09, 公開日: 1989-10-09, 最終更新日: 2024-05-22)

主引用文献

Chen, Z.G.,Stauffacher, C.,Li, Y.,Schmidt, T.,Bomu, W.,Kamer, G.,Shanks, M.,Lomonossoff, G.,Johnson, J.E.
Protein-RNA interactions in an icosahedral virus at 3.0 A resolution.
Science, 245:154-159, 1989

PubMed Abstract: Nearly 20 percent of the packaged RNA in bean-pod mottle virus (BPMV) binds to the capsid interior in a symmetric fashion and is clearly visible in the electron density map. The RNA displaying icosahedral symmetry is single-stranded with well-defined polarity and stereochemical properties. Interactions with protein are dominated by nonbonding forces with few specific contacts. The tertiary and quaternary structures of the BPMV capsid proteins are similar to those observed in animal picornaviruses, supporting the close relation between plant comoviruses and animal picornaviruses established by previous biological studies.

PubMed: 2749253

実験手法

X-RAY DIFFRACTION (3 Å)