1BMN

HUMAN ALPHA-THROMBIN COMPLEXED WITH [S-(R*,R*)]-1-(AMINOIMINOMETHYL)-N-[[1-[N-[(2-NAPHTHALENYLSULFONYL)-L-SERYL]-PYRROLIDINYL]METHYL]-3-PIPERIDENECARBOXAMIDE (BMS-189090)

1BMN の概要

• エントリーDOI: 10.2210/pdb1bmn/pdb
• 分子名称: ALPHA-THROMBIN, HIRUDIN I, [S-(R*,R*)]-1-(AMINOIMINOMETHYL)-N-[[1-[N-[(2-NAPHTHALENYLSULFONYL)-L-SERYL]-3-PYRROLIDINYL]METHYL]-3-PIPERIDENECARBOXAMIDE, ... (5 entities in total)
• 機能のキーワード: hydrolase, complex (serine protease-inhibitor), hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Secreted, extracellular space: P00734 P00734; Secreted: P28507
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 35875.91

構造登録者

Malley, M.,Sack, J. (登録日: 1995-11-14, 公開日: 1996-12-07, 最終更新日: 2011-07-13)

• 主引用文献: Malley, M.F.,Tabernero, L.,Chang, C.Y.,Ohringer, S.L.,Roberts, D.G.,Das, J.,Sack, J.S.; Crystallographic determination of the structures of human alpha-thrombin complexed with BMS-186282 and BMS-189090.; Protein Sci., 5:221-228, 1996; PubMed: 8745399

実験手法

X-RAY DIFFRACTION (2.8 Å)