1BLX

P19INK4D/CDK6 COMPLEX

1BLX の概要

• エントリーDOI: 10.2210/pdb1blx/pdb
• 分子名称: CYCLIN-DEPENDENT KINASE 6, P19INK4D, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: inhibitor protein, cyclin-dependent kinase, cell cycle control, alpha/beta, complex (inhibitor protein-kinase), complex (inhibitor protein-kinase) complex, complex (inhibitor protein/kinase)
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 54859.78

構造登録者

Brotherton, D.H.,Dhanaraj, V.,Wick, S.,Brizuela, L.,Domaille, P.J.,Volyanik, E.,Xu, X.,Parisini, E.,Smith, B.O.,Archer, S.J.,Serrano, M.,Brenner, S.L.,Blundell, T.L.,Laue, E.D. (登録日: 1998-07-21, 公開日: 1999-06-01, 最終更新日: 2024-05-22)

• 主引用文献: Brotherton, D.H.,Dhanaraj, V.,Wick, S.,Brizuela, L.,Domaille, P.J.,Volyanik, E.,Xu, X.,Parisini, E.,Smith, B.O.,Archer, S.J.,Serrano, M.,Brenner, S.L.,Blundell, T.L.,Laue, E.D.; Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d.; Nature, 395:244-250, 1998; PubMed: 9751051; DOI: 10.1038/26164

実験手法

X-RAY DIFFRACTION (1.9 Å)