1BLL

X-RAY CRYSTALLOGRAPHIC DETERMINATION OF THE STRUCTURE OF BOVINE LENS LEUCINE AMINOPEPTIDASE COMPLEXED WITH AMASTATIN: FORMULATION OF A CATALYTIC MECHANISM FEATURING A GEM-DIOLATE TRANSITION STATE

1BLL の概要

• エントリーDOI: 10.2210/pdb1bll/pdb
• 関連するBIRD辞書のPRD_ID: PRD_000415
• 分子名称: LEUCINE AMINOPEPTIDASE, AMASTATIN, ZINC ION, ... (4 entities in total)
• 機能のキーワード: alpha-aminoacylpeptide, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Bos taurus (bovine); 詳細
• 細胞内の位置: Cytoplasm: P00727
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 53573.50

構造登録者

Kim, H.,Lipscomb, W.N. (登録日: 1993-03-02, 公開日: 1994-01-31, 最終更新日: 2023-11-15)

• 主引用文献: Kim, H.,Lipscomb, W.N.; X-ray crystallographic determination of the structure of bovine lens leucine aminopeptidase complexed with amastatin: formulation of a catalytic mechanism featuring a gem-diolate transition state.; Biochemistry, 32:8465-8478, 1993; PubMed: 8357796; DOI: 10.1021/bi00084a011

実験手法

X-RAY DIFFRACTION (2.4 Å)