1BL7
THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB220025
Summary for 1BL7
Entry DOI | 10.2210/pdb1bl7/pdb |
Descriptor | PROTEIN (MAP KINASE P38), 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE (3 entities in total) |
Functional Keywords | transferase, inhibitor, map kinase, serine/ threonine-protein kinase, p38 |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm (By similarity): Q16539 |
Total number of polymer chains | 1 |
Total formula weight | 43721.73 |
Authors | Wang, Z.,Canagarajah, B.J.,Boehm, J.C.,Kassis, S.,Cobb, M.H.,Young, P.R.,Abdel-Meguid, S.,Adams, J.L.,Goldsmith, E.J. (deposition date: 1998-07-23, release date: 1999-07-26, Last modification date: 2024-04-03) |
Primary citation | Wang, Z.,Canagarajah, B.J.,Boehm, J.C.,Kassisa, S.,Cobb, M.H.,Young, P.R.,Abdel-Meguid, S.,Adams, J.L.,Goldsmith, E.J. Structural basis of inhibitor selectivity in MAP kinases. Structure, 6:1117-1128, 1998 Cited by PubMed: 9753691DOI: 10.1016/S0969-2126(98)00113-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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