1BFZ

BOUND CONFORMATION OF N-TERMINAL CLEAVAGE PRODUCT PEPTIDE MIMIC (P1-P9 OF RELEASE SITE) WHILE BOUND TO HCMV PROTEASE AS DETERMINED BY TRANSFERRED NOESY EXPERIMENTS (P1-P5 SHOWN ONLY), NMR, 32 STRUCTURES

1BFZ の概要

• エントリーDOI: 10.2210/pdb1bfz/pdb
• 分子名称: HCMV PROTEASE R-SITE N-TERMINAL CLEAVAGE PRODUCT (1 entity in total)
• 機能のキーワード: substriate cleavage, bound conformation, extended conformation, substrate-based competitive inhibitor design, peptide
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 593.69

構造登録者

Laplante, S.R.,Aubry, N.,Bonneau, P.R.,Cameron, D.R.,Lagace, L.,Massariol, M.-J.,Montpetit, H.,Ploufe, C.,Kawai, S.H.,Fulton, B.D.,Chen, Z.,Ni, F. (登録日: 1998-05-25, 公開日: 1999-05-25, 最終更新日: 2011-07-13)

• 主引用文献: LaPlante, S.R.,Aubry, N.,Bonneau, P.R.,Cameron, D.R.,Lagace, L.,Massariol, M.J.,Montpetit, H.,Plouffe, C.,Kawai, S.H.,Fulton, B.D.,Chen, Z.,Ni, F.; Human cytomegalovirus protease complexes its substrate recognition sequences in an extended peptide conformation.; Biochemistry, 37:9793-9801, 1998; PubMed: 9657693; DOI: 10.1021/bi980555v

実験手法

SOLUTION NMR