1BE2

LIPID TRANSFER PROTEIN COMPLEXED WITH PALMITATE, NMR, 10 STRUCTURES

1BE2 の概要

• エントリーDOI: 10.2210/pdb1be2/pdb
• 分子名称: LIPID TRANSFER PROTEIN, PALMITIC ACID (2 entities in total)
• 機能のキーワード: lipid transport, lipid transfer protein, palmitate
• 由来する生物種: Hordeum vulgare
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 9961.39

構造登録者

Lerche, M.H.,Poulsen, F.M. (登録日: 1998-05-19, 公開日: 1998-12-02, 最終更新日: 2024-11-20)

主引用文献

Lerche, M.H.,Poulsen, F.M.
Solution structure of barley lipid transfer protein complexed with palmitate. Two different binding modes of palmitate in the homologous maize and barley nonspecific lipid transfer proteins.
Protein Sci., 7:2490-2498, 1998

PubMed Abstract: The structure of a nonspecific lipid transfer protein from barley (ns-LTPbarley) in complex with palmitate has been determined by NMR spectroscopy. The structure has been compared to the structure of ns-LTPbarley in the absence of palmitate, to the structure of ns-LTPbarley in complex with palmitoyl coenzyme A, to the structure of ns-LTPmaize in its free form, and to the maize protein complexed with palmitate. Binding of palmitate only affects the structure of ns-LTPbarley moderately in contrast to the binding of palmitoyl coenzyme A, which leads to a considerable expansion of the protein. The modes of binding palmitate to the maize and barley protein are different. Although in neither case there are major conformational changes in the protein, the orientation of the palmitate in the two proteins is exactly opposite.

PubMed: 9865943

実験手法

SOLUTION NMR