1BDM

THE STRUCTURE AT 1.8 ANGSTROMS RESOLUTION OF A SINGLE SITE MUTANT (T189I) OF MALATE DEHYDROGENASE FROM THERMUS FLAVUS WITH INCREASED ENZYMATIC ACTIVITY

1BDM の概要

• エントリーDOI: 10.2210/pdb1bdm/pdb
• 分子名称: MALATE DEHYDROGENASE, BETA-6-HYDROXY-1,4,5,6-TETRHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE (3 entities in total)
• 機能のキーワード: oxidoreductase(nad(a)-choh(d))
• 由来する生物種: Thermus thermophilus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72296.40

構造登録者

Kelly, C.A.,Birktoft, J.J. (登録日: 1993-02-16, 公開日: 1994-12-20, 最終更新日: 2024-02-07)

• 主引用文献: Kelly, C.A.,Nishiyama, M.,Ohnishi, Y.,Beppu, T.,Birktoft, J.J.; Determinants of protein thermostability observed in the 1.9-A crystal structure of malate dehydrogenase from the thermophilic bacterium Thermus flavus.; Biochemistry, 32:3913-3922, 1993; PubMed: 8471603; DOI: 10.1021/bi00066a010

実験手法

X-RAY DIFFRACTION (1.8 Å)