1BBZ

CRYSTAL STRUCTURE OF THE ABL-SH3 DOMAIN COMPLEXED WITH A DESIGNED HIGH-AFFINITY PEPTIDE LIGAND: IMPLICATIONS FOR SH3-LIGAND INTERACTIONS

1BBZ の概要

• エントリーDOI: 10.2210/pdb1bbz/pdb
• 分子名称: ABL TYROSINE KINASE, PEPTIDE P41, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: complex (transferase-peptide), signal transduction, sh3 domain, complex (transferase-peptide) complex, complex (transferase/peptide)
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm, cytoskeleton. Isoform IB: Nucleus membrane; Lipid-anchor: P00519
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 30217.17

構造登録者

Pisabarro, M.T.,Serrano, L.,Wilmanns, M. (登録日: 1998-04-28, 公開日: 1998-11-25, 最終更新日: 2023-08-02)

• 主引用文献: Pisabarro, M.T.,Serrano, L.,Wilmanns, M.; Crystal structure of the abl-SH3 domain complexed with a designed high-affinity peptide ligand: implications for SH3-ligand interactions.; J.Mol.Biol., 281:513-521, 1998; PubMed: 9698566; DOI: 10.1006/jmbi.1998.1932

実験手法

X-RAY DIFFRACTION (1.65 Å)