1B8Y

X-RAY STRUCTURE OF HUMAN STROMELYSIN CATALYTIC DOMAIN COMPLEXED WITH NON-PEPTIDE INHIBITORS: IMPLICATIONS FOR INHIBITOR SELECTIVITY

1B8Y の概要

• エントリーDOI: 10.2210/pdb1b8y/pdb
• 分子名称: PROTEIN (STROMELYSIN-1), ZINC ION, CALCIUM ION, ... (6 entities in total)
• 機能のキーワード: hydrolase, matrix metalloproteinase-3, stromelysin-1
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Secreted, extracellular space, extracellular matrix : P08254
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 19511.48

構造登録者

Pavlovsky, A.G.,Williams, M.G.,Ye, Q.-Z.,Ortwine, D.F.,Purchase II, C.F.,White, A.D.,Dhanaraj, V.,Roth, B.D.,Johnson, L.L.,Hupe, D.,Humblet, C.,Blundell, T.L. (登録日: 1999-02-03, 公開日: 1999-08-31, 最終更新日: 2023-12-27)

• 主引用文献: Pavlovsky, A.G.,Williams, M.G.,Ye, Q.Z.,Ortwine, D.F.,Purchase II, C.F.,White, A.D.,Dhanaraj, V.,Roth, B.D.,Johnson, L.L.,Hupe, D.,Humblet, C.,Blundell, T.L.; X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity.; Protein Sci., 8:1455-1462, 1999; PubMed: 10422833

実験手法

X-RAY DIFFRACTION (2 Å)