1B4Q

Solution structure of human thioltransferase complex with glutathione

1B4Q の概要

• エントリーDOI: 10.2210/pdb1b4q/pdb
• 分子名称: PROTEIN (HUMAN THIOLTRANSFERASE), GLUTATHIONE (2 entities in total)
• 機能のキーワード: human thioltransferase, disulfide intermediate, glutathione, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm: P35754
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 11899.58

構造登録者

Yang, Y.,Jao, S.C.,Nanduri, S.,Starke, D.W.,Mieyal, J.J.,Qin, J. (登録日: 1998-12-25, 公開日: 1999-12-23, 最終更新日: 2023-12-27)

• 主引用文献: Yang, Y.,Jao, S.,Nanduri, S.,Starke, D.W.,Mieyal, J.J.,Qin, J.; Reactivity of the human thioltransferase (glutaredoxin) C7S, C25S, C78S, C82S mutant and NMR solution structure of its glutathionyl mixed disulfide intermediate reflect catalytic specificity.; Biochemistry, 37:17145-17156, 1998; PubMed: 9860827; DOI: 10.1021/bi9806504

実験手法

SOLUTION NMR