1B4J

COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY

1B4J の概要

• エントリーDOI: 10.2210/pdb1b4j/pdb
• 分子名称: ANTIBODY (2 entities in total)
• 機能のキーワード: antibody engineering, humanized and chimeric antibodies, fab, x-ray structures, gamma-interferon
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 47089.50

構造登録者

Fan, Z.,Shan, L.,Goldsteen, B.Z.,Guddat, L.W.,Thakur, A.,Landolfi, N.F.,Co, M.S.,Vasques, M.,Queen, C.,Ramsland, P.A.,Edmundson, A.B. (登録日: 1998-12-22, 公開日: 1999-06-15, 最終更新日: 2023-08-02)

• 主引用文献: Fan, Z.C.,Shan, L.,Goldsteen, B.Z.,Guddat, L.W.,Thakur, A.,Landolfi, N.F.,Co, M.S.,Vasquez, M.,Queen, C.,Ramsland, P.A.,Edmundson, A.B.; Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.; J.Mol.Recog., 12:19-32, 1999; PubMed: 10398393; DOI: 10.1002/(SICI)1099-1352(199901/02)12:1<19::AID-JMR445>3.3.CO;2-P

実験手法

X-RAY DIFFRACTION (2.9 Å)