1B2Y
STRUCTURE OF HUMAN PANCREATIC ALPHA-AMYLASE IN COMPLEX WITH THE CARBOHYDRATE INHIBITOR ACARBOSE
Summary for 1B2Y
Entry DOI | 10.2210/pdb1b2y/pdb |
Descriptor | Pancreatic alpha-amylase, alpha-D-quinovopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | human alpha-amylase, acarbose, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Secreted, extracellular space: P04746 |
Total number of polymer chains | 1 |
Total formula weight | 56798.58 |
Authors | Nahoum, V.,Payan, F. (deposition date: 1998-12-03, release date: 2000-02-16, Last modification date: 2023-09-20) |
Primary citation | Nahoum, V.,Roux, G.,Anton, V.,Rouge, P.,Puigserver, A.,Bischoff, H.,Henrissat, B.,Payan, F. Crystal structures of human pancreatic alpha-amylase in complex with carbohydrate and proteinaceous inhibitors. Biochem.J., 346 Pt 1:201-208, 2000 Cited by PubMed: 10657258DOI: 10.1042/0264-6021:3460201 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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