1B0S

BINDING OF AR-1-144, A TRI-IMIDAZOLE DNA MINOR GROOVE BINDER, TO CCGG SEQUENCE ANALYZED BY NMR SPECTROSCOPY

1B0S の概要

• エントリーDOI: 10.2210/pdb1b0s/pdb
• NMR情報: BMRB: 4392
• 分子名称: DNA (5'-D(*GP*AP*AP*CP*CP*GP*GP*TP*TP*C)-3'), (2-{[4-({4-[(4-FORMYLAMINO-1-METHYL-1H-IMIDAZOLE-2-CARBONYL)-AMINO]-1-METHYL-1H-IMIDAZOLE-2-CARBONYL}-AMINO)-1-METHYL-1 H-IMIDAZOLE-2-CARBONYL]-AMINO}-ETHYL)-DIMETHYL-AMMONIUM (2 entities in total)
• 機能のキーワード: anticancer drug, drug design, dna structure, sequence specific recognition, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 7063.03

構造登録者

Yang, X.-L.,Kaenzig, C.,Lee, M.,Wang, A.H.-J. (登録日: 1998-11-12, 公開日: 1999-08-31, 最終更新日: 2023-12-27)

• 主引用文献: Yang, X.L.,Kaenzig, C.,Lee, M.,Wang, A.H.; Binding of AR-1-144, a tri-imidazole DNA minor groove binder, to CCGG sequence analyzed by NMR spectroscopy.; Eur.J.Biochem., 263:646-655, 1999; PubMed: 10469127; DOI: 10.1046/j.1432-1327.1999.00515.x

実験手法

SOLUTION NMR