1AZE

NMR STRUCTURE OF THE COMPLEX BETWEEN THE C32S-Y7V MUTANT OF THE NSH3 DOMAIN OF GRB2 WITH A PEPTIDE FROM SOS, 10 STRUCTURES

1AZE の概要

• エントリーDOI: 10.2210/pdb1aze/pdb
• 分子名称: GRB2, SOS (2 entities in total)
• 機能のキーワード: complex (adaptor protein-peptide), sh3 domain, guanine-nucleotide releasing factor, complex (adaptor protein-peptide) complex, complex (adaptor protein/peptide)
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 7650.74

構造登録者

Vidal, M.,Gincel, E.,Goudreau, N.,Cornille, F.,Parker, F.,Duchesne, M.,Tocque, B.,Garbay, C.,Roques, B.P. (登録日: 1997-11-17, 公開日: 1999-05-18, 最終更新日: 2021-11-03)

• 主引用文献: Vidal, M.,Goudreau, N.,Cornille, F.,Cussac, D.,Gincel, E.,Garbay, C.; Molecular and cellular analysis of Grb2 SH3 domain mutants: interaction with Sos and dynamin.; J.Mol.Biol., 290:717-730, 1999; PubMed: 10395825; DOI: 10.1006/jmbi.1999.2899

実験手法

SOLUTION NMR