1AXL
SOLUTION CONFORMATION OF THE (-)-TRANS-ANTI-[BP]DG ADDUCT OPPOSITE A DELETION SITE IN DNA DUPLEX D(CCATC-[BP]G-CTACC)D(GGTAG--GATGG), NMR, 6 STRUCTURES
Summary for 1AXL
Entry DOI | 10.2210/pdb1axl/pdb |
Descriptor | DNA DUPLEX D(CCATC-[BP]G-CTACC)D(GGTAG--GATGG), 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE (3 entities in total) |
Functional Keywords | deoxyribonucleic acid, dna, benzo[a]pyrene, carcinogen |
Total number of polymer chains | 2 |
Total formula weight | 6723.55 |
Authors | Feng, B.,Gorin, A.A.,Kolbanovskiy, A.,Hingerty, B.E.,Geacintov, N.E.,Broyde, S.,Patel, D.J. (deposition date: 1997-10-16, release date: 1998-07-01, Last modification date: 2024-05-22) |
Primary citation | Feng, B.,Gorin, A.,Kolbanovskiy, A.,Hingerty, B.E.,Geacintov, N.E.,Broyde, S.,Patel, D.J. Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove. Biochemistry, 36:13780-13790, 1997 Cited by PubMed: 9374854DOI: 10.1021/bi970070r PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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