1AXL

SOLUTION CONFORMATION OF THE (-)-TRANS-ANTI-[BP]DG ADDUCT OPPOSITE A DELETION SITE IN DNA DUPLEX D(CCATC-[BP]G-CTACC)D(GGTAG--GATGG), NMR, 6 STRUCTURES

1AXL の概要

• エントリーDOI: 10.2210/pdb1axl/pdb
• 分子名称: DNA DUPLEX D(CCATC-[BP]G-CTACC)D(GGTAG--GATGG), 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE (3 entities in total)
• 機能のキーワード: deoxyribonucleic acid, dna, benzo[a]pyrene, carcinogen
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 6723.55

構造登録者

Feng, B.,Gorin, A.A.,Kolbanovskiy, A.,Hingerty, B.E.,Geacintov, N.E.,Broyde, S.,Patel, D.J. (登録日: 1997-10-16, 公開日: 1998-07-01, 最終更新日: 2022-02-16)

• 主引用文献: Feng, B.,Gorin, A.,Kolbanovskiy, A.,Hingerty, B.E.,Geacintov, N.E.,Broyde, S.,Patel, D.J.; Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove.; Biochemistry, 36:13780-13790, 1997; PubMed: 9374854; DOI: 10.1021/bi970070r

実験手法

SOLUTION NMR