1AX8
Human obesity protein, leptin
Summary for 1AX8
Entry DOI | 10.2210/pdb1ax8/pdb |
Descriptor | OBESITY PROTEIN (2 entities in total) |
Functional Keywords | helical cytokine, hematopoietic factor, diabetes, obesity, cytokine |
Biological source | Homo sapiens (human) |
Cellular location | Secreted: P41159 |
Total number of polymer chains | 1 |
Total formula weight | 15984.30 |
Authors | Zhang, F.,Beals, J.M.,Briggs, S.L.,Clawson, D.K.,Wery, J.-P.,Schevitz, R.W. (deposition date: 1997-10-31, release date: 1998-11-25, Last modification date: 2012-05-09) |
Primary citation | Zhang, F.,Basinski, M.B.,Beals, J.M.,Briggs, S.L.,Churgay, L.M.,Clawson, D.K.,DiMarchi, R.D.,Furman, T.C.,Hale, J.E.,Hsiung, H.M.,Schoner, B.E.,Smith, D.P.,Zhang, X.Y.,Wery, J.P.,Schevitz, R.W. Crystal structure of the obese protein leptin-E100. Nature, 387:206-209, 1997 Cited by PubMed: 9144295DOI: 10.1038/387206a0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report