1ATU
UNCLEAVED ALPHA-1-ANTITRYPSIN
Summary for 1ATU
| Entry DOI | 10.2210/pdb1atu/pdb |
| Descriptor | ALPHA-1-ANTITRYPSIN (1 entity in total) |
| Functional Keywords | serine protease inhibitor, alpha-1-antitrypsin, conformational transition, loop flexibility, metastability, stabilizing mutations |
| Biological source | Homo sapiens (human) |
| Cellular location | Secreted. Short peptide from AAT: Secreted, extracellular space, extracellular matrix: P01009 |
| Total number of polymer chains | 1 |
| Total formula weight | 42046.09 |
| Authors | Ryu, S.-E.,Choi, H.-J. (deposition date: 1997-05-11, release date: 1997-08-20, Last modification date: 2023-08-02) |
| Primary citation | Ryu, S.E.,Choi, H.J.,Kwon, K.S.,Lee, K.N.,Yu, M.H. The native strains in the hydrophobic core and flexible reactive loop of a serine protease inhibitor: crystal structure of an uncleaved alpha1-antitrypsin at 2.7 A. Structure, 4:1181-1192, 1996 Cited by PubMed: 8939743DOI: 10.1016/S0969-2126(96)00126-8 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
Download full validation report
