1AK4

HUMAN CYCLOPHILIN A BOUND TO THE AMINO-TERMINAL DOMAIN OF HIV-1 CAPSID

1AK4 の概要

• エントリーDOI: 10.2210/pdb1ak4/pdb
• 分子名称: CYCLOPHILIN A, HIV-1 CAPSID (3 entities in total)
• 機能のキーワード: capsid, hiv-1, cyclophilin a, isomerase, rotamase complex (capsid protein-cyclosporin), viral protein-isomerase complex, viral protein/isomerase
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: P62937; Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12497
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 68308.00

構造登録者

Hill, C.P.,Gamble, T.R.,Vajdos, F.F.,Worthylake, D.K.,Sundquist, W.I. (登録日: 1997-05-28, 公開日: 1997-10-15, 最終更新日: 2023-08-02)

• 主引用文献: Gamble, T.R.,Vajdos, F.F.,Yoo, S.,Worthylake, D.K.,Houseweart, M.,Sundquist, W.I.,Hill, C.P.; Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid.; Cell(Cambridge,Mass.), 87:1285-1294, 1996; PubMed: 8980234; DOI: 10.1016/S0092-8674(00)81823-1

実験手法

X-RAY DIFFRACTION (2.36 Å)