1AJ7
IMMUNOGLOBULIN 48G7 GERMLINE FAB ANTIBODY COMPLEXED WITH HAPTEN 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID. AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY
Summary for 1AJ7
| Entry DOI | 10.2210/pdb1aj7/pdb |
| Descriptor | IMMUNOGLOBULIN 48G7 FAB (LIGHT CHAIN), IMMUNOGLOBULIN 48G7 FAB (HEAVY CHAIN), 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID (3 entities in total) |
| Functional Keywords | germline antibody, fab, catalytic antibody, affinity maturation, immunoglobulin |
| Biological source | Mus musculus (house mouse) More |
| Total number of polymer chains | 2 |
| Total formula weight | 46829.93 |
| Authors | Wedemayer, G.J.,Wang, L.H.,Patten, P.A.,Schultz, P.G.,Stevens, R.C. (deposition date: 1997-05-15, release date: 1997-11-12, Last modification date: 2023-08-02) |
| Primary citation | Wedemayer, G.J.,Patten, P.A.,Wang, L.H.,Schultz, P.G.,Stevens, R.C. Structural insights into the evolution of an antibody combining site. Science, 276:1665-1669, 1997 Cited by PubMed: 9180069DOI: 10.1126/science.276.5319.1665 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
Download full validation report
