1AI3

ORBITAL STEERING IN THE CATALYTIC POWER OF ENZYMES: SMALL STRUCTURAL CHANGES WITH LARGE CATALYTIC CONSEQUENCES

Summary for 1AI3

Entry DOI	10.2210/pdb1ai3/pdb
Descriptor	ISOCITRATE DEHYDROGENASE, NICOTINAMIDE-(6-DEAMINO-6-HYDROXY-ADENINE)-DINUCLEOTIDE PHOSPHATE, ISOCITRIC ACID, ... (5 entities in total)
Functional Keywords	oxidoreductase (nad(a)-choh(d)), nadp, phosphorylation, glyoxylate bypass, oxidoreductase
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	46770.38
Authors	Stoddard, B.L.,Mesecar, A.,Koshland Junior, D.E. (deposition date: 1997-04-30, release date: 1997-11-12, Last modification date: 2023-08-02)
Primary citation	Mesecar, A.D.,Stoddard, B.L.,Koshland Jr., D.E. Orbital steering in the catalytic power of enzymes: small structural changes with large catalytic consequences. Science, 277:202-206, 1997 Cited by PubMed: 9211842 DOI: 10.1126/science.277.5323.202 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation