1AI3

ORBITAL STEERING IN THE CATALYTIC POWER OF ENZYMES: SMALL STRUCTURAL CHANGES WITH LARGE CATALYTIC CONSEQUENCES

1AI3 の概要

• エントリーDOI: 10.2210/pdb1ai3/pdb
• 分子名称: ISOCITRATE DEHYDROGENASE, NICOTINAMIDE-(6-DEAMINO-6-HYDROXY-ADENINE)-DINUCLEOTIDE PHOSPHATE, ISOCITRIC ACID, ... (5 entities in total)
• 機能のキーワード: oxidoreductase (nad(a)-choh(d)), nadp, phosphorylation, glyoxylate bypass, oxidoreductase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 46770.38

構造登録者

Stoddard, B.L.,Mesecar, A.,Koshland Junior, D.E. (登録日: 1997-04-30, 公開日: 1997-11-12, 最終更新日: 2023-08-02)

• 主引用文献: Mesecar, A.D.,Stoddard, B.L.,Koshland Jr., D.E.; Orbital steering in the catalytic power of enzymes: small structural changes with large catalytic consequences.; Science, 277:202-206, 1997; PubMed: 9211842; DOI: 10.1126/science.277.5323.202

実験手法

X-RAY DIFFRACTION (1.9 Å)