1AI1

HIV-1 V3 LOOP MIMIC

1AI1 の概要

• エントリーDOI: 10.2210/pdb1ai1/pdb
• 分子名称: IGG1-KAPPA 59.1 FAB (LIGHT CHAIN), IGG1-KAPPA 59.1 FAB (HEAVY CHAIN), AIB142 (3 entities in total)
• 機能のキーワード: complex (antibody-peptide), antibody, constrained hiv-1 v3 loop peptide, immunoglobulin, complex (antibody-peptide) complex, complex (antibody/peptide)
• 由来する生物種: Mus musculus (house mouse); 詳細
• 細胞内の位置: Isoform Secreted: Secreted: P01868; Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P05877
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 50711.86

構造登録者

Ghiara, J.B.,Wilson, I.A. (登録日: 1996-11-06, 公開日: 1997-05-15, 最終更新日: 2023-08-02)

• 主引用文献: Ghiara, J.B.,Ferguson, D.C.,Satterthwait, A.C.,Dyson, H.J.,Wilson, I.A.; Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site.; J.Mol.Biol., 266:31-39, 1997; PubMed: 9054968; DOI: 10.1006/jmbi.1996.0768

実験手法

X-RAY DIFFRACTION (2.8 Å)