1AI1

HIV-1 V3 LOOP MIMIC

1AI1 の概要

分子名称IGG1-KAPPA 59.1 FAB (LIGHT CHAIN), IGG1-KAPPA 59.1 FAB (HEAVY CHAIN), AIB142 (3 entities in total)
機能のキーワードcomplex (antibody-peptide), antibody, constrained hiv-1 v3 loop peptide, immunoglobulin, complex (antibody-peptide) complex, complex (antibody/peptide)
由来する生物種Mus musculus (house mouse)
細胞内の位置Isoform Secreted: Secreted P01868
Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein P05877
ポリマー鎖数3
分子量合計50711.86
構造登録者
Ghiara, J.B.,Wilson, I.A. (登録日: 1996-11-06, 公開日: 1997-05-15, 最終更新日: 2011-07-13)
主引用文献
Ghiara, J.B.,Ferguson, D.C.,Satterthwait, A.C.,Dyson, H.J.,Wilson, I.A.
Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site.
J.Mol.Biol., 266:31-39, 1997
PubMed: 9054968 (主引用文献が同じPDBエントリー)
DOI: 10.1006/jmbi.1996.0768
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.8 Å)
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構造検証レポート

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers261.8%15.5%2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード