1AH4
PIG ALDOSE REDUCTASE, HOLO FORM
Summary for 1AH4
Entry DOI | 10.2210/pdb1ah4/pdb |
Descriptor | ALDOSE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total) |
Functional Keywords | oxidoreductase, aldose reductase, inhibition, diabetes |
Biological source | Sus scrofa (pig) |
Cellular location | Cytoplasm: P80276 |
Total number of polymer chains | 1 |
Total formula weight | 36567.44 |
Authors | Moras, D.,Podjarny, A. (deposition date: 1997-04-12, release date: 1998-04-15, Last modification date: 2024-04-03) |
Primary citation | Urzhumtsev, A.,Tete-Favier, F.,Mitschler, A.,Barbanton, J.,Barth, P.,Urzhumtseva, L.,Biellmann, J.F.,Podjarny, A.,Moras, D. A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil. Structure, 5:601-612, 1997 Cited by PubMed: 9195881DOI: 10.1016/S0969-2126(97)00216-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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