1AGU

THE SOLUTION NMR STRUCTURE OF THE C10R ADDUCT OF BENZO[A]PYRENE-DIOL-EPOXIDE AT THE N6 POSITION OF ADENINE OF AN 11 BASE-PAIR OLIGONUCLEOTIDE SEQUENCE CODING FOR AMINO ACIDS 60-62 OF THE PRODUCT OF THE N-RAS PROTOONCOGENE, MINIMIZED AVERAGE STRUCTURE

1AGU の概要

• エントリーDOI: 10.2210/pdb1agu/pdb
• 分子名称: DNA (5'-D(*CP*GP*GP*AP*CP*EP*AP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3') (2 entities in total)
• 機能のキーワード: dna duplex, human n-ras gene, codon 61 sequence, c10r-bpde adduct, intercalation, n6-adenine adduct, deoxyribonucleic acid, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 7009.73

構造登録者

Zegar, I.S.,Stone, M.P. (登録日: 1997-03-25, 公開日: 1997-08-20, 最終更新日: 2024-05-22)

• 主引用文献: Zegar, I.S.,Kim, S.J.,Johansen, T.N.,Horton, P.J.,Harris, C.M.,Harris, T.M.,Stone, M.P.; Adduction of the human N-ras codon 61 sequence with (-)-(7S,8R,9R,10S)-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a] pyrene: structural refinement of the intercalated SRSR(61,2) (-)-(7S,8R,9S,1 0R)-N6-[10-(7,8,9,10- tetrahydrobenzo[a]pyrenyl)]-2'-deoxyadenosyl adduct from 1H NMR; Biochemistry, 35:6212-6224, 1996; PubMed: 8639561; DOI: 10.1021/bi9524732

実験手法

SOLUTION NMR