1AF9

TETANUS NEUROTOXIN C FRAGMENT

Summary for 1AF9

• Entry DOI: 10.2210/pdb1af9/pdb
• Descriptor: TETANUS NEUROTOXIN (2 entities in total)
• Functional Keywords: clostridial neurotoxin, tetanus, receptor binding
• Biological source: Clostridium tetani
• Total number of polymer chains: 1
• Total formula weight: 51826.43

Authors

Umland, T.C.,Wingert, L.,Swaminathan, S.,Furey, W.F.,Schmidt, J.J.,Sax, M. (deposition date: 1997-03-24, release date: 1998-04-29, Last modification date: 2024-02-07)

Primary citation

Umland, T.C.,Wingert, L.M.,Swaminathan, S.,Furey, W.F.,Schmidt, J.J.,Sax, M.
Structure of the receptor binding fragment HC of tetanus neurotoxin.
Nat.Struct.Biol., 4:788-792, 1997

PubMed Abstract: The 2.7 A structure of the tetanus neurotoxin receptor binding fragment Hc reveals a jelly-roll domain and a beta-trefoil domain. Hc retains the unique transport properties of the holotoxin and is capable of eliciting a protective immunological response against the full length holotoxin.

PubMed: 9334741
DOI: 10.1038/nsb1097-788

Experimental method

X-RAY DIFFRACTION (2.7 Å)