1AE5

HUMAN HEPARIN BINDING PROTEIN

1AE5 の概要

• エントリーDOI: 10.2210/pdb1ae5/pdb
• 分子名称: HEPARIN BINDING PROTEIN, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: serine protease homolog, endotoxin binding, heparin binding, inflammation, antibacterial, cap37, azurocidin, glycosylated protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24744.89

構造登録者

Iversen, L.F.,Kastrup, J.S.,Bjorn, S.E.,Rasmussen, P.B.,Wiberg, F.C.,Flodgaard, H.J.,Larsen, I.K. (登録日: 1997-03-05, 公開日: 1998-03-11, 最終更新日: 2024-12-25)

主引用文献

Iversen, L.F.,Kastrup, J.S.,Bjorn, S.E.,Rasmussen, P.B.,Wiberg, F.C.,Flodgaard, H.J.,Larsen, I.K.
Structure of HBP, a multifunctional protein with a serine proteinase fold.
Nat.Struct.Biol., 4:265-268, 1997

PubMed Abstract: The structure of human heparin binding protein reveals that the serine proteinase fold has been used as a scaffold for a multifunctional protein with antibacterial activity, monocyte and t-cell activating properties and endotoxin and heparin binding capacity.

PubMed: 9095193
DOI: 10.1038/nsb0497-265

実験手法

X-RAY DIFFRACTION (2.3 Å)