1AE4

ALDEHYDE REDUCTASE COMPLEXED WITH COFACTOR AND INHIBITOR, ALPHA CARBON ATOMS ONLY

Summary for 1AE4

DescriptorALDEHYDE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TOLRESTAT (3 entities in total)
Functional Keywordsaldo-keto reductase, oxidoreductase, tim-barrel
Biological sourceSus scrofa (pig)
Total number of polymer chains1
Total molecular weight37684.64
Authors
El-Kabbani, O. (deposition date: 1997-03-05, release date: 1998-03-11, Last modification date: 2011-07-13)
Primary citation
el-Kabbani, O.,Carper, D.A.,McGowan, M.H.,Devedjiev, Y.,Rees-Milton, K.J.,Flynn, T.G.
Studies on the inhibitor-binding site of porcine aldehyde reductase: crystal structure of the holoenzyme-inhibitor ternary complex.
Proteins, 29:186-192, 1997
PubMed: 9329083 (PDB entries with the same primary citation)
DOI: 10.1002/(SICI)1097-0134(199710)29:2<186::AID-PROT6>3.0.CO;2-B
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.4 Å)
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Structure validation

Clashscore7MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1ae4
no rotation
Molmil generated image of 1ae4
rotated about x axis by 90°
Molmil generated image of 1ae4
rotated about y axis by 90°