1AE4
ALDEHYDE REDUCTASE COMPLEXED WITH COFACTOR AND INHIBITOR, ALPHA CARBON ATOMS ONLY
Summary for 1AE4
Entry DOI | 10.2210/pdb1ae4/pdb |
Descriptor | ALDEHYDE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TOLRESTAT (3 entities in total) |
Functional Keywords | aldo-keto reductase, oxidoreductase, tim-barrel |
Biological source | Sus scrofa (pig) |
Total number of polymer chains | 1 |
Total formula weight | 37684.64 |
Authors | El-Kabbani, O. (deposition date: 1997-03-05, release date: 1998-03-11, Last modification date: 2024-04-03) |
Primary citation | el-Kabbani, O.,Carper, D.A.,McGowan, M.H.,Devedjiev, Y.,Rees-Milton, K.J.,Flynn, T.G. Studies on the inhibitor-binding site of porcine aldehyde reductase: crystal structure of the holoenzyme-inhibitor ternary complex. Proteins, 29:186-192, 1997 Cited by PubMed: 9329083DOI: 10.1002/(SICI)1097-0134(199710)29:2<186::AID-PROT6>3.0.CO;2-B PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
Download full validation report