1AE4

ALDEHYDE REDUCTASE COMPLEXED WITH COFACTOR AND INHIBITOR, ALPHA CARBON ATOMS ONLY

1AE4 の概要

• エントリーDOI: 10.2210/pdb1ae4/pdb
• 分子名称: ALDEHYDE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TOLRESTAT (3 entities in total)
• 機能のキーワード: aldo-keto reductase, oxidoreductase, tim-barrel
• 由来する生物種: Sus scrofa (pig)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 37684.64

構造登録者

El-Kabbani, O. (登録日: 1997-03-05, 公開日: 1998-03-11, 最終更新日: 2024-04-03)

• 主引用文献: el-Kabbani, O.,Carper, D.A.,McGowan, M.H.,Devedjiev, Y.,Rees-Milton, K.J.,Flynn, T.G.; Studies on the inhibitor-binding site of porcine aldehyde reductase: crystal structure of the holoenzyme-inhibitor ternary complex.; Proteins, 29:186-192, 1997; PubMed: 9329083; DOI: 10.1002/(SICI)1097-0134(199710)29:2<186::AID-PROT6>3.0.CO;2-B

実験手法

X-RAY DIFFRACTION (2.4 Å)