1A84
NMR SOLUTION STRUCTURE OF A DNA DODECAMER DUPLEX CONTAINING A CIS-DIAMMINEPLATINUM(II) D(GPG) INTRASTRAND CROSS-LINK, THE MAJOR ADDUCT OF THE ANTICANCER DRUG CISPLATIN, 1 STRUCTURE
Summary for 1A84
Entry DOI | 10.2210/pdb1a84/pdb |
Descriptor | DNA D(CCTCTG*G*TCTCC), DNA D(GGAGACCAGAGG), Cisplatin (3 entities in total) |
Functional Keywords | deoxyribonucleic acid, cisplatin, dna, duplex, dodecamer, hmg-domain interaction |
Total number of polymer chains | 2 |
Total formula weight | 7626.83 |
Authors | Gelasco, A.,Lippard, S.J. (deposition date: 1998-04-02, release date: 1998-11-25, Last modification date: 2024-04-10) |
Primary citation | Gelasco, A.,Lippard, S.J. NMR solution structure of a DNA dodecamer duplex containing a cis-diammineplatinum(II) d(GpG) intrastrand cross-link, the major adduct of the anticancer drug cisplatin. Biochemistry, 37:9230-9239, 1998 Cited by PubMed: 9649303DOI: 10.1021/bi973176v PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
Download full validation report