1A71

TERNARY COMPLEX OF AN ACTIVE SITE DOUBLE MUTANT OF HORSE LIVER ALCOHOL DEHYDROGENASE, PHE93=>TRP, VAL203=>ALA WITH NAD AND TRIFLUOROETHANOL

1A71 の概要

• エントリーDOI: 10.2210/pdb1a71/pdb
• 分子名称: LIVER ALCOHOL DEHYDROGENASE, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (5 entities in total)
• 機能のキーワード: oxidoreductase (nad(a)-choh(d)), liver, alcohol, dehydrogenase, ladh, active site mutant, oxidoreductase
• 由来する生物種: Equus caballus (horse)
• 細胞内の位置: Cytoplasm: P00327
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 81517.08

構造登録者

Colby, T.D.,Bahnson, B.J.,Chin, J.K.,Klinman, J.P.,Goldstein, B.M. (登録日: 1998-03-19, 公開日: 1998-06-17, 最終更新日: 2024-05-22)

• 主引用文献: Colby, T.D.,Bahnson, B.J.,Chin, J.K.,Klinman, J.P.,Goldstein, B.M.; Active site modifications in a double mutant of liver alcohol dehydrogenase: structural studies of two enzyme-ligand complexes.; Biochemistry, 37:9295-9304, 1998; PubMed: 9649310; DOI: 10.1021/bi973184b

実験手法

X-RAY DIFFRACTION (2 Å)