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1A5S

CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH 5-FLUOROINDOLE PROPANOL PHOSPHATE AND L-SER BOUND AS AMINO ACRYLATE TO THE BETA SITE

Summary for 1A5S
Entry DOI10.2210/pdb1a5s/pdb
DescriptorTRYPTOPHAN SYNTHASE (ALPHA CHAIN), TRYPTOPHAN SYNTHASE (BETA CHAIN), 5-FLUOROINDOLE PROPANOL PHOSPHATE, ... (7 entities in total)
Functional Keywordslyase, carbon-oxygen lyase, tryptophan biosynthesis, pyridoxal phosphate, complex (lyase-inhibitor), complex (lyase-inhibitor) complex, complex (lyase/inhibitor)
Biological sourceSalmonella typhimurium
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Total number of polymer chains2
Total formula weight72336.22
Authors
Schneider, T.R.,Gerhardt, E.,Lee, M.,Liang, P.-H.,Anderson, K.S.,Schlichting, I. (deposition date: 1998-02-17, release date: 1999-03-30, Last modification date: 2023-08-02)
Primary citationSchneider, T.R.,Gerhardt, E.,Lee, M.,Liang, P.H.,Anderson, K.S.,Schlichting, I.
Loop closure and intersubunit communication in tryptophan synthase.
Biochemistry, 37:5394-5406, 1998
Cited by
PubMed: 9548921
DOI: 10.1021/bi9728957
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.3 Å)
Structure validation

217705

数据于2024-03-27公开中

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