1A5S

CRYSTAL STRUCTURE OF WILD-TYPE TRYPTOPHAN SYNTHASE COMPLEXED WITH 5-FLUOROINDOLE PROPANOL PHOSPHATE AND L-SER BOUND AS AMINO ACRYLATE TO THE BETA SITE

1A5S の概要

• エントリーDOI: 10.2210/pdb1a5s/pdb
• 分子名称: TRYPTOPHAN SYNTHASE (ALPHA CHAIN), TRYPTOPHAN SYNTHASE (BETA CHAIN), 5-FLUOROINDOLE PROPANOL PHOSPHATE, ... (7 entities in total)
• 機能のキーワード: lyase, carbon-oxygen lyase, tryptophan biosynthesis, pyridoxal phosphate, complex (lyase-inhibitor), complex (lyase-inhibitor) complex, complex (lyase/inhibitor)
• 由来する生物種: Salmonella typhimurium; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72336.22

構造登録者

Schneider, T.R.,Gerhardt, E.,Lee, M.,Liang, P.-H.,Anderson, K.S.,Schlichting, I. (登録日: 1998-02-17, 公開日: 1999-03-30, 最終更新日: 2024-05-22)

• 主引用文献: Schneider, T.R.,Gerhardt, E.,Lee, M.,Liang, P.H.,Anderson, K.S.,Schlichting, I.; Loop closure and intersubunit communication in tryptophan synthase.; Biochemistry, 37:5394-5406, 1998; PubMed: 9548921; DOI: 10.1021/bi9728957

実験手法

X-RAY DIFFRACTION (2.3 Å)