1A3P

ROLE OF THE 6-20 DISULFIDE BRIDGE IN THE STRUCTURE AND ACTIVITY OF EPIDERMAL GROWTH FACTOR, NMR, 20 STRUCTURES

Summary for 1A3P

DescriptorEPIDERMAL GROWTH FACTOR (1 entity in total)
Functional Keywordsgrowth factor, murine epidermal growth factor, disulfide connectivities, egf-like domain
Biological sourceMus musculus (house mouse)
Cellular locationMembrane; Single-pass type I membrane protein P01132
Total number of polymer chains1
Total molecular weight4878.4
Authors
Barnham, K.,Torres, A.,Alewood, D.,Alewood, P.,Domagala, T.,Nice, E.,Norton, R. (deposition date: 1998-01-22, release date: 1998-07-29, Last modification date: 2018-03-14)
Primary citation
Barnham, K.J.,Torres, A.M.,Alewood, D.,Alewood, P.F.,Domagala, T.,Nice, E.C.,Norton, R.S.
Role of the 6-20 disulfide bridge in the structure and activity of epidermal growth factor.
Protein Sci., 7:1738-1749, 1998
PubMed: 10082370 (PDB entries with the same primary citation)
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers4411.6%40.0%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures