1A1E

C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-PHOSPHOTYR-GLU-(3-BUTYLPIPERIDINE)

Summary for 1A1E

• Entry DOI: 10.2210/pdb1a1e/pdb
• Descriptor: C-SRC TYROSINE KINASE, ACE-PHOSPHOTYR-GLU-(3-BUTYLPIPERIDINE) (3 entities in total)
• Functional Keywords: complex (transferase-peptide), complex (transferase-peptide) complex, complex (transferase/peptide)
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane : P12931
• Total number of polymer chains: 4
• Total formula weight: 25686.89

Authors

Shewchuk, L.,Jordan, S. (deposition date: 1997-12-10, release date: 1998-04-08, Last modification date: 2023-08-02)

• Primary citation: Charifson, P.S.,Shewchuk, L.M.,Rocque, W.,Hummel, C.W.,Jordan, S.R.,Mohr, C.,Pacofsky, G.J.,Peel, M.R.,Rodriguez, M.,Sternbach, D.D.,Consler, T.G.; Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study.; Biochemistry, 36:6283-6293, 1997; PubMed: 9174343; DOI: 10.1021/bi970019n

Experimental method

X-RAY DIFFRACTION (2.2 Å)