1A1D
YEAST RNA POLYMERASE SUBUNIT RPB8, NMR, MINIMIZED AVERAGE STRUCTURE, ALPHA CARBONS ONLY
Summary for 1A1D
| Entry DOI | 10.2210/pdb1a1d/pdb |
| Descriptor | RNA POLYMERASE (1 entity in total) |
| Functional Keywords | rpb8, rna polymerase, ob fold, eukaryotic, yeast, nucleotidyltransferase |
| Biological source | Saccharomyces cerevisiae (baker's yeast) |
| Cellular location | Nucleus: P20436 |
| Total number of polymer chains | 1 |
| Total formula weight | 16525.36 |
| Authors | Krapp, S.,Kelly, G.,Reischl, J.,Weinzierl, R.,Matthews, S. (deposition date: 1997-12-10, release date: 1999-03-02, Last modification date: 2024-04-10) |
| Primary citation | Krapp, S.,Kelly, G.,Reischl, J.,Weinzierl, R.O.,Matthews, S. Eukaryotic RNA polymerase subunit RPB8 is a new relative of the OB family. Nat.Struct.Biol., 5:110-114, 1998 Cited by PubMed Abstract: RNA polymerase II subunit RPB8 is an essential subunit that is highly conserved throughout eukaryotic evolution and is present in all three types of nuclear RNA polymerases. We report the first high resolution structural insight into eukaryotic RNA polymerase architecture with the solution structure of RPB8 from Saccharomyces cerevisiae. It consists of an eight stranded, antiparallel beta-barrel, four short helical regions and a large, unstructured omega-loop. The strands are connected in classic Greek-key fashion. The overall topology is unusual and contains a striking C2 rotational symmetry. Furthermore, it is most likely a novel associate of the oligonucleotide/oligosaccharide (OB) binding protein class. PubMed: 9461075DOI: 10.1038/nsb0298-110 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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