1A08
C-SRC (SH2 DOMAIN) COMPLEXED WITH ACE-DIFLUORO PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE)
Summary for 1A08
Entry DOI | 10.2210/pdb1a08/pdb |
Descriptor | C-SRC TYROSINE KINASE, ACE-DIFLUORO PHOSPHOTYR-GLU-(N,N-DIPENTYL AMINE) (3 entities in total) |
Functional Keywords | complex (transferase-peptide), complex (transferase-peptide) complex, complex (transferase/peptide) |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane : P12931 |
Total number of polymer chains | 4 |
Total formula weight | 25786.99 |
Authors | Shewchuk, L.,Jordan, S. (deposition date: 1997-12-09, release date: 1998-04-08, Last modification date: 2023-08-02) |
Primary citation | Charifson, P.S.,Shewchuk, L.M.,Rocque, W.,Hummel, C.W.,Jordan, S.R.,Mohr, C.,Pacofsky, G.J.,Peel, M.R.,Rodriguez, M.,Sternbach, D.D.,Consler, T.G. Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study. Biochemistry, 36:6283-6293, 1997 Cited by PubMed: 9174343DOI: 10.1021/bi970019n PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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